Article

Extensive phylogenies of human development reveal variable embryonic patterns

2020-11-26

Abstract excerpt

<h4>ABSTRACT</h4> Starting from the zygote, all cells in the developing and adult human body continuously acquire mutations. A mutation shared between two different cells implies a shared progenitor cell and can thus be used as a naturally occurring marker for lineage tracing. Here, we reconstruct extensive phylogenies of normal tissues from three adult individuals using whole-genome sequencing of 511 laser captu...

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Literature Corpus work: abd5de88-e638-590b-bef5-5cf38f514fc0
DOI: 10.1101/2020.11.25.397828

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