Article

Clonal dynamics in early human embryogenesis inferred from somatic mutation

2020-11-24

Abstract excerpt

<h4>Summary</h4> The trillions of cells that constitute the human body are developed from a fertilized egg through embryogenesis. However, cellular dynamics and developmental outcomes of embryonic cells in humans remain to be largely unknown due to the technical and ethical challenges. Here, we explored whole-genomes of 334 single-cell expanded clones and targeted deep-sequences of 379 bulk tissues obtained from...

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Literature Corpus work: 11728923-4757-529a-b97f-c2059ab0b974
DOI: 10.1101/2020.11.23.395244

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