Article

A novel wild-derived MHC-linked locus regulates host immunity to gammaherpesvirus infection

2026-06-28

Abstract excerpt

Inefficient host control of infection by gammaherpesviruses is a risk factor for lymphoproliferative disease, autoimmunity, and cancer, yet naturally occurring genetic determinants of viral control remain poorly defined. Previously, we discovered that wild-derived PWD/PhJ (PWD) mice exhibit markedly improved control of murine gammaherpesvirus 68 (MHV-68) replication compared with C57BL/6J (B6) mice. This elite con...

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Literature Corpus work: abd4ed14-589a-58a1-b573-059e8f96c6b8
DOI: 10.64898/2026.06.23.733957

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