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Article

Adaptive immune response to West Nile virus infection in the Collaborative Cross mouse model: A database of cellular phenotypes and Quantitative Trait Loci.

Scientific data - 21 Nov 2025

Chamberlin Steven, Graham Jessica, Jeng Sophia, Swarts Jessica, Ferris Martin, Heise Mark, Baric Ralph S, McWeeney Shannon, Lund Jennifer, Mooney Michael

Abstract excerpt

West Nile virus (WNV) infection can lead to a wide range of clinical outcomes, from asymptomatic to self-limiting febrile and serious neuro-invasive disease. Knowledge of the genetic factors contributing to the heterogeneity of this disease can inform pathogenic mechanisms, help guidethe development of cell based therapeutics, vaccines and inform lifestyle choices. Yet this knowledge is incomplete in humans. Here...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41271835
DOI: 10.1038/s41597-025-06293-x
PMCID: PMC12749056

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