Article
How the Virus Outsmarts the Host: Function and Structure of Cytomegalovirus MHC‐I‐Like Molecules in the Evasion of Natural Killer Cell Surveillance
1 Jan 2011
Abstract excerpt
Natural killer (NK) cells provide an initial host immune response to infection by many viral pathogens. Consequently, the viruses have evolved mechanisms to attenuate the host response, leading to improved viral fitness. One mechanism employed by members of the β-herpesvirus family, which includes the cytomegaloviruses, is to modulate the expression of cell surface ligands recognized by NK cell activation...