Article

Activation, control and T-bet+ B cell-mediated immune surveillance of endogenous retroviruses

2023-03-23

Abstract excerpt

<title>Abstract</title> <p>Endogenous retroviruses (ERVs) are an integral part of the mammalian genome. The role of immune control of ERVs in general is poorly defined as is their role as anti-cancer immune targets or drivers of autoimmune disease. Here, we generated mouse-strains where Moloney-Murine Leukemia Virus tagged with GFP (ERV-GFP) infected the murine germline. This enabled us to analyze the role of gen...

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Literature Corpus work: c9d99836-1b65-53b3-8327-06d45455620f
DOI: 10.21203/rs.3.rs-2666493/v1

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