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Therapeutic DNA Vaccine Targeting <i>Mycobacterium tuberculosis</i> Persisters Shortens Curative Tuberculosis Treatment

2024-09-07

Abstract excerpt

Mycobacterium tuberculosis ( Mtb) is one of the leading infectious causes of death worldwide. There is no available licensed therapeutic vaccine that shortens active tuberculosis (TB) disease drug treatment and prevents relapse, despite the World Health Organization’s calls. Here, we show that an intranasal DNA vaccine containing a fusion of the stringent response rel Mtb gene with the gene encoding the immature...

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Literature Corpus work
ab4f0641-fd8d-57e2-81da-0a1efb5d5fa4
DOI
10.1101/2024.09.03.611055
Open publication

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Therapeutic DNA Vaccine Targeting <i>Mycobacterium tuberculosis</i> Persisters Shortens Curative Tuberculosis TreatmentDOI 10.1101/2024.09.03.611055
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