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Hybrid Bacterial Membrane Nanovaccine Reprograms the Tuberculosis Immune Microenvironment via CD40 to Surpass BCG Protection

2026-06-01

Abstract excerpt

<title>Abstract</title> <p> Tuberculosis (TB) remains a leading cause of death worldwide, partly because current vaccines provide limited protection against adult pulmonary disease. This limitation is associated with ineffective antigen presentation and immune tolerance induced by <italic>Mycobacterium tuberculosis</italic> (Mtb). To address this challenge, we developed ME-NPs, a biomimetic nanovaccine compose...

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Literature Corpus work
ab917060-137a-576b-8891-cc8927f110ed
DOI
10.21203/rs.3.rs-9659638/v1
Open publication

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Hybrid Bacterial Membrane Nanovaccine Reprograms the Tuberculosis Immune Microenvironment via CD40 to Surpass BCG ProtectionDOI 10.21203/rs.3.rs-9659638/v1
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