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Bronchus associated lymphoid tissue induced by an attenuated <i>Mycobacterium tuberculosis</i> vaccine prevents tuberculosis from heterologous TB challenge

2026-05-26

Abstract excerpt

Tuberculosis (TB) remains a leading cause of death from infectious disease worldwide, underscoring the urgent need for vaccines with greater and more consistent efficacy than Bacille Calmette–Guérin (BCG). We previously showed that mucosal vaccination with an isogenic Mycobacterium tuberculosis ( Mtb ) mutant lacking the stress-response transcription factor SigH ( ΔsigH ) prevents pulmonary TB in two macaque sp...

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Literature Corpus work
7d4016a5-6f20-5c97-bd37-722a8a1e763c
DOI
10.64898/2026.05.21.726618
Open publication

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Bronchus associated lymphoid tissue induced by an attenuated <i>Mycobacterium tuberculosis</i> vaccine prevents tuberculosis from heterologous TB challengeDOI 10.64898/2026.05.21.726618
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