Article

Developing next-generation tuberculosis vaccines based on pathogen–host interactions: Towards a holistic perspective

2025-01-07

Abstract excerpt

Tuberculosis (TB), caused by the highly complex intracellular pathogen Mycobacterium tuberculosis (Mtb), remains a leading burden on global health and the economy. Vaccines represent the most economically effective approach to preventing and controlling infectious diseases. Currently, Bacillus Calmette–Guérin (BCG) is the only available vaccine for TB, which protects infants and young children from disseminated an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eb7f3fc1-807a-5354-8dcf-7b53b04f2ffc
DOI: 10.1016/j.hlife.2024.11.003

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Developing next-generation tuberculosis vaccines based on pathogen–host interactions: Towards a holistic perspectiveDOI 10.1016/j.hlife.2024.11.003Read

A vaccine for global eradication of TB - A novel conceptual framework and design of a potent peptide-based vaccine with universal coverage through advanced computational vaccinologySemantic proximity Read

Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape TownSemantic proximity Read

Tuberculosis: What We Don’t Know Can, and Does, Hurt UsSemantic proximity Read

Advances in protein subunit vaccines against tuberculosisSemantic proximity Read

A Mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-GuérinSemantic proximity Read

Host-Pathogen Interaction as a Novel Target for Host-Directed Therapies in TuberculosisSemantic proximity Read

Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human DiseasesSemantic proximity Read

Immunoinformatics and structural aided approach to develop multi-epitope based subunit vaccine against Mycobacterium tuberculosisSemantic proximity Read

A Review on T Cell Epitopes Identified Using Prediction and Cell-Mediated Immune Models for Mycobacterium tuberculosis and Bordetella pertussisSemantic proximity Read

Host Immune Response to Mycobacterium tuberculosis Infection: Implications for Vaccine DevelopmentSemantic proximity Read

Manipulation of BCG vaccine: a double-edged swordSemantic proximity Read

Novel In Silico mRNA vaccine design exploiting proteins of M. tuberculosis that modulates host immune responses by inducing epigenetic modificationsSemantic proximity Read