Article

Clonal hematopoiesis is enriched in melanoma and associated with genotype-specific differences in tumor growth and survival

2026-07-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The clinical significance of clonal hematopoiesis of indeterminate potential (CHIP) in melanoma remains incompletely defined, particularly with respect to CHIP genotype, clone size, and somatic mutations (e.g BRAF mutations). We integrated human cohort data and a syngeneic melanoma mouse model to evaluate whether CHIP is associated with melanoma risk, tumor growth, and diff...

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Literature Corpus work: aaf1bd98-d74d-5e8c-abb6-3772a2ee7f61
DOI: 10.64898/2026.07.13.26357981

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