Back to search

Article

<i>TERT</i> expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities

2023-01-26

Abstract excerpt

Telomerase reverse transcriptase ( TERT ) promoter mutations occur frequently in cancer, have been associated with increased TERT expression and cell proliferation, and could potentially influence therapeutic regimens for melanoma. As the role of TERT expression in malignant melanoma and the non-canonical functions of TERT remain understudied, we aimed to extend the current knowledge on both types of TERT alte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
da5c5f0f-f27e-5268-8295-66180c992ca2
DOI
10.1101/2023.01.25.525565
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>TERT</i> expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entitiesDOI 10.1101/2023.01.25.525565
TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities.Semantic proximity
TERT Promoter Mutations and Telomerase in MelanomaSemantic proximity
TERT and TERT promoter in melanocytic neoplasms: Current concepts in pathogenesis, diagnosis, and prognosis.Semantic proximity
TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti-CTLA4 treatment.Semantic proximity
TERT mutations in Malignant Melanoma-Survival Meta-AnalysisSemantic proximity
Genetic and Epigenetic Alterations of TERT Are Associated with Inferior Outcome in Adolescent and Young Adult Patients with MelanomaSemantic proximity
Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulationSemantic proximity
Using deep learning to decipher the impact of telomerase promoter mutations on the dynamic metastatic morpholome.Semantic proximity
TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma.Semantic proximity
TERT promoter mutations and melanoma survival: A comprehensive literature review and meta-analysis.Semantic proximity
<scp><i>TERT</i></scp> promoter mutations in melanoma survivalSemantic proximity
Associations between TERT Promoter Mutations and Survival in Superficial Spreading and Nodular Melanomas in a Large Prospective Patient Cohort.Semantic proximity
Select a neighboring publication to make it the new centre.