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Mutational Architecture of Clonal Hematopoiesis of Indeterminate Potential in 29,596 Chinese Individuals

2026-04-17

Abstract excerpt

<title>Abstract</title> <p>Clonal hematopoiesis of indeterminate potential (CHIP) an age-related expansion of hematopoietic clones with somatic mutations, associated with hematologic malignancies and cardiovascular disease, but remains poorly characterized beyond European-ancestry populations. Here, we analyzed high-depth sequencing data from 29,596 individuals, including a discovery cohort of 13,445 and an indep...

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Literature Corpus work
058dc951-3bf0-51ba-8d92-354298de10cf
DOI
10.21203/rs.3.rs-9041912/v1
Open publication

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Mutational Architecture of Clonal Hematopoiesis of Indeterminate Potential in 29,596 Chinese IndividualsDOI 10.21203/rs.3.rs-9041912/v1
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