Article
Multi-model preclinical platform predicts clinical response of melanoma to immunotherapy
2019-08-06
Abstract excerpt
Although immunotherapy has revolutionized cancer treatment, only a subset of patients demonstrates durable clinical benefit. Definitive predictive biomarkers and targets to overcome resistance remain unidentified, underscoring the urgency to develop reliable immunocompetent models for mechanistic assessment. Here we characterize a panel of syngeneic mouse models representing the main molecular and phenotypic subty...
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Identifiers and source
- Literature Corpus work
- 5ddbc6a7-e57c-519f-b379-307414e0d0e0
- DOI
- 10.1101/727826