Article

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy

2026-05-30

Abstract excerpt

<h4>ABSTRACT</h4> In the United States, sickle cell disease (SCD) is a rare inherited hemoglobinopathy affecting about 100,000 individuals, mostly with African ancestry. SCD causes damage to multiple organ systems and SCD nephropathy (SCDN) is a common complication associated with early mortality. We previously performed a genome-wide association study (GWAS) for SCDN and identified a modest number of genome-wide...

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Literature Corpus work: aa88766e-91ed-5e58-a3d6-643e07cb34d9
DOI: 10.64898/2026.05.27.26354213

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