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Article

Systematic Review of Genetic Modifiers Associated with the Development and/or Progression of Nephropathy in Patients with Sickle Cell Disease.

International journal of molecular sciences - 16 May 2024

Labarque Veerle, Okocha Emmanuel Chide

Abstract excerpt

Sickle cell nephropathy (SCN) is a common complication of sickle cell disease (SCD) that significantly contributes to morbidity and mortality. In addition to clinical and life-style factors, genetic variants influence this risk. We performed a systematic review, searching five databases. Studies evaluating the effect of genetic modifiers on SCN were eligible. Twenty-eight studies (fair-to-good quality) were...

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Share to Anemia, Sickle Cell
Share to Apolipoprotein L1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome-Wide Association Study

Share to Glomerular Filtration Rate

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Identifiers

PMID: 38791464
DOI: 10.3390/ijms25105427
PMCID: PMC11121490

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