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Article

Clinical and Genetic Predictors of Sickle Cell Nephropathy: A Global Systematic Review.

Omics : a journal of integrative biology - 1 Aug 2025

Banda Kambe, Nguweneza Arthemon, Mnika Khuthala, Nembaware Victoria, Chagaluka George, Wonkam Ambroise

Abstract excerpt

Sickle cell disease (SCD) affects nearly 300,000 newborns annually worldwide, with 80% born in Africa. Sickle cell nephropathy (SCN) affects 5-18% of patients with SCD and contributes significantly to morbidity and mortality. Identifying SCN-associated factors would promote effective clinical management. We conducted a global systematic review in accordance with the Preferred Reporting Items for Systematic Review...

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Topics

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Share to Anemia, Sickle Cell
Share to Apolipoprotein L1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome-Wide Association Study

Share to Heme Oxygenase-1

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Source

Identifiers

PMID: 40719369
DOI: 10.1177/15578100251359276

Genes

APOL1
SCD
HMOX1
TNNI3K
ADAMTS7
CRYL1
FPGT
LRP1B
VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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