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Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

22 Dec 2023

Abstract excerpt

Chronic kidney disease is a leading cause of death and disability globally and impacts individuals of African ancestry (AFR) or with ancestry in the Americas (AMS) who are under-represented in genome-wide association studies (GWASs) of kidney function. To address this bias, we conducted a large meta-analysis of GWASs of estimated glomerular filtration rate (eGFR) in 145,732 AFR and AMS individuals. We identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38190104
DOI: 10.1016/j.xgen.2023.100468

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