Article

From GWAS to Translational Insights: Comprehensive Genetic Analysis of Nephrotic Syndrome from Multiple Populations

2025-10-08

Abstract excerpt

<title>Abstract</title> <p> Nephrotic syndrome is a rare, heterogeneous kidney disorder characterized by proteinuria, hypoalbuminemia, and edema. To elucidate its genetic architecture, we conducted a large-scale, electronic health record (EHR)-linked, multi-ancestry genome-wide association study comprising 5,214 cases and 1,601,060 controls. We identified 37 distinct loci associated with disease risk, including...

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Literature Corpus work: ead08575-daf9-5d88-9972-d4e560479f3a
DOI: 10.21203/rs.3.rs-7482306/v1

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