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Article

Genetics, Genomics, and Precision Medicine in End-Stage Kidney Disease.

Seminars in nephrology - 1 Jul 2018

Kopp Jeffrey B, Winkler Cheryl A

Abstract excerpt

Recent advances in genetics of renal disease have deepened our understanding of progressive kidney disease. Here, we review genetic variants that are of particular importance to progressive glomerular disease that result in end-stage kidney disease (ESKD). Some of the most striking findings relate to APOL1 genetic variants, seen exclusively in individuals of sub-Saharan African descent, that create a...

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Identifiers

PMID: 30082052
DOI: 10.1016/j.semnephrol.2018.05.002
PMCID: PMC8351533

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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