Article
Meta-analysis of African ancestry genome-wide association studies identified novel locus and validates multiple loci associated with kidney function.
BMC genomics - 29 Aug 2023
Kintu Christopher, Soremekun Opeyemi, Machipisa Tafadzwa, Mayanja Richard, Kalyesubula Robert, Bagaya Bernard S, Jjingo Daudi, Chikowore Tinashe, Fatumo Segun
Abstract excerpt
Despite recent efforts to increase diversity in genome-wide association studies (GWASs), most loci currently associated with kidney function are still limited to European ancestry due to the underlying sample selection bias in available GWASs. We set out to identify susceptibility loci associated with estimated glomerular filtration rate (eGFRcrea) in 80027 individuals of African-ancestry from the UK Biobank...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
