Article

Testing for phylogenetic signal in single-cell RNA-seq data

2021-01-08

Abstract excerpt

Phylogenetic methods are emerging as a useful tool to understand cancer evolutionary dynamics, including tumor structure, heterogeneity, and progression. Most currently used approaches utilize either bulk whole genome sequencing (WGS) or single-cell DNA sequencing (scDNA-seq) and are based on calling copy number alterations and single nucleotide variants (SNVs). scRNA-seq is commonly applied to explore differentia...

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Literature Corpus work: a930772b-92a7-5fb2-9286-3c19ee74dbb1
DOI: 10.1101/2021.01.07.425804

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