Article

Unraveling the phylogenetic signal of gene expression from single-cell RNA-seq data

2024-04-20

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of phenotypic heterogeneity. Although the predominant focus of scRNA-seq analyses has been assessing gene expression changes, several approaches have been proposed in recent years to identify changes at the DNA level from scRNA-seq data. In this study, we evaluated the relative performance of six strategies for calling single-nucleotide varia...

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Literature Corpus work: 14532bc4-5f6a-5ca4-b7e0-9adfbdfecf25
DOI: 10.1101/2024.04.17.589871

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