Article

A Nanovial-Based Platform for Functional Discovery of Antigen-Reactive TCRs from Unconventional T Cells

2025-08-07

Abstract excerpt

Unconventional T cells, such as mucosal-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells, recognize non-peptide antigens presented by MR1 and CD1d, respectively, and play pivotal roles in immunity, allowing targeting of cells based on metabolic activity. Although components of the T cell receptors (TCRs) for these unconventional T cells are invariant, significant variability in the C...

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Literature Corpus work: a846212d-bfe4-5dcd-95ed-a1da4ec52fb3
DOI: 10.1101/2025.08.06.668816

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