Article

Systematic discovery of receptor-ligand biology by engineered cell entry and single-cell genomics

2021-12-14

Abstract excerpt

<h4>ABSTRACT</h4> Cells communicate with each other via receptor-ligand interactions on the cell surface. Here we describe a technology for l e ntiviral-mediated cell e nt ry by e ngineered r eceptor-ligand interaction (ENTER) to decode receptor specificity. Engineered lentiviral particles displaying specific ligands deliver fluorescent proteins into target cells upon cognate receptor-ligand interaction, with...

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Literature Corpus work: 0135e6ea-ec6a-5793-88d6-2cbe6f00314c
DOI: 10.1101/2021.12.13.472464

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