Article

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

2017-05-05

Abstract excerpt

Tumor-infiltrating lymphocytes (TILs) are critical to anti-cancer immune responses, but their diverse phenotypes and functions remain poorly understood and challenging to study. We therefore developed a single-cell barcoding technology for deep characterization of TILs without the need for cell-sorting or culture. Our emulsion-based method captures full-length, natively paired B-cell and T-cell receptor (BCR and T...

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Literature Corpus work: 19acbb31-7c5d-587b-b205-8719fcb54f1e
DOI: 10.1101/134841

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