Article

Sequential <i>in vivo</i> labeling of insulin secretory granule pools in INS-SNAP transgenic pigs

2021-04-23

Abstract excerpt

β-cells produce, store and secrete insulin upon elevated blood glucose levels. Insulin secretion is a highly regulated process. The probability for insulin secretory granules to undergo fusion with the plasma membrane or being degraded is correlated with their age. However, the molecular features and stimuli connected to this behavior have not yet been fully understood. Furthermore, our understanding of β-cell fun...

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Literature Corpus work: a799761a-d6db-514c-96e1-3e8fe7065300
DOI: 10.1101/2021.04.23.441054

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