Article

HLA-F expression on CD4 T cells in HIV-1 is linked to the presence of viremia and modulated by KIR3DS1

2025-03-25

Abstract excerpt

<title>Abstract</title> <p><italic>KIR3DS1</italic> is an activating natural killer (NK) cell receptor gene– present in 10-40% of humans– and is associated with extended AIDS-free survival. Although its ligand HLA-F has been identified, the underlying protective mechanism in HIV-1 is not yet understood. We sought to uncover the role of the KIR3DS1/HLA-F axis through investigating HLA-F surface and transcriptional...

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Literature Corpus work: a7929a25-9845-5290-9e11-81fa2c06c007
DOI: 10.21203/rs.3.rs-6203704/v1

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