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Article

Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.

Immunology and cell biology - 1 Jan 2015

Zipperlen Katrin, Gallant Maureen, Stapleton Staci, Heath John, Barrett Lisa, Grant Michael

Abstract excerpt

Certain human class I histocompatibility-linked leukocyte antigen (HLA)/killer cell immunoglobulin-like receptor (KIR) genotypic combinations confer more favourable prognoses upon exposure to human immunodeficiency virus (HIV). These combinations influence natural killer (NK) cell function, thereby implicating NK cells in protection from HIV infection or disease progression. Because CD8(+) T cells restrict HIV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-A Antigens

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Share to Receptors, KIR3DL1

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Source

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Identifiers

PMID: 25112829
DOI: 10.1038/icb.2014.68
PMCID: PMC4500641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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