Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa.

The Journal of infectious diseases - 16 Apr 2019

Mori Masahiko, Leitman Ellen, Walker Bruce, Ndung'u Thumbi, Carrington Mary, Goulder Philip

Abstract excerpt

BACKGROUND: HLA class I contributes to HIV immune control through antigen presentation to cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. In contrast to investigations of CTL, studies of NK cells in HIV control through HLA-killer immunoglobulin-like receptor (KIR) interactions remain sparse in African cohorts. METHODS: Treatment-naive, chronically HIV-infected adults (N = 312) were recruited from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4 Lymphocyte Count
Share to Genes, MHC Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-C Antigens

Share to HLA-E Antigens

Share to NK Cell Lectin-Like Receptor Subfamily C

Share to Receptors, KIR2DL1

Share to Receptors, KIR2DL3

Share to South Africa

Source

Open in PubMed Open full text

Identifiers

PMID: 30520960
DOI: 10.1093/infdis/jiy692
PMCID: PMC6467198

Genes

KIR2DL3
CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa.PMID 30520960Read ↗

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.Semantic proximity Read ↗

Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.Semantic proximity Read ↗

Natural killer cell-mediated innate sieve effect on HIV-1: the impact of KIR/HLA polymorphism on HIV-1 subtype-specific acquisition in east Africa.Semantic proximity Read ↗

Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.Semantic proximity Read ↗

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa.Semantic proximity Read ↗

Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.Semantic proximity Read ↗

Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression.Semantic proximity Read ↗

Immunogenetics of HIV disease.Semantic proximity Read ↗

Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands.Semantic proximity Read ↗

High KIR diversity in Uganda and Botswana children living with HIVSemantic proximity Read ↗

Variations in KIR genes: a study in HIV-1 serodiscordant couples.Semantic proximity Read ↗

KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.