Article
Under representation of the inhibitory KIR3DL1 molecule and the KIR3DL1+/BW4+ complex in HIV exposed seronegative individuals.
The Journal of infectious diseases - 1 May 2011
Guerini Franca Rosa, Lo Caputo Sergio, Gori Andrea, Bandera Alessandra, Mazzotta Francesco, Uglietti Alessia, Zanzottera Milena, Maserati Renato, Clerici Mario
Abstract excerpt
The activation of natural killer (NK) cells is modulated by surface molecules. We analyzed NK cells in human immunodeficiency virus (HIV)-exposed seronegative (HESN) individuals by means of molecular typing of HLA B, Cw, and killer cell immunoglobulin-like receptor (KIR) molecules. In HESN individuals, compared with HIV patients, the frequency of the inhibitory KIR3DL1 allele and of the KIR3DL1(+)/Bw4(+)...
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