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Article

KIR2DS4 promotes HIV-1 pathogenesis: new evidence from analyses of immunogenetic data and natural killer cell function.

PloS one - 1 Jan 2014

Merino Aimee M, Dugast Anne-Sophie, Wilson Craig M, Goepfert Paul A, Alter Galit, Kaslow Richard A, Tang Jianming

Abstract excerpt

BACKGROUND: KIR2DS4 gene variants encode full-length and truncated protein products, with only the former serving as membrane-bound receptors to activate natural killer (NK) cells. We have previously shown that full-length KIR2DS4 was associated with relatively high viral load and accelerated het...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24901871
DOI: 10.1371/journal.pone.0099353
PMCID: PMC4047121

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MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24901871-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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