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Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolution

2022-12-30

Abstract excerpt

<h4>Summary</h4> The broad application of single-cell RNA sequencing has revealed transcriptional cell state heterogeneity across diverse healthy and malignant somatic tissues. Recent advances in lineage tracing technologies have further enabled the simultaneous capture of cell transcriptional state along with cellular ancestry thus enabling the study of somatic evolution at an unprecedented resolution; however,...

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Literature Corpus work
a73d5773-a407-5e31-bcd4-2395e7971063
DOI
10.1101/2022.12.28.522128
Open publication

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Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolutionDOI 10.1101/2022.12.28.522128
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