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Leveraging single‐cell sequencing to unravel intratumour heterogeneity and tumour evolution in human cancers

19 Apr 2022

Abstract excerpt

Intratumour heterogeneity (ITH) and tumour evolution are well-documented phenomena in human cancers. While the advent of next-generation sequencing technologies has facilitated the large-scale capture of genomic data, the field of single-cell genomics is nascent but rapidly advancing and generating many new insights into the complex molecular mechanisms of tumour biology. In this review, we provide an overview of...

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PMID: 35438189
DOI: 10.1002/path.5914

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