Article

Mitochondrial clone tracing within spatially intact human tissues

2025-07-17

Abstract excerpt

Understanding tissue development and intra-tissue evolution requires the ability to trace clones in intact tissues coupled with high-plex molecular profiling preserving spatial context. However, current lineage tracing tools are incompatible with spatial omics. Here, we present SUMMIT (Spatially Unveiling Mitochondrial Mutations In Tissues), a spatially-resolved lineage tracing technology that integrates gene expr...

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Literature Corpus work: e9dbf6c8-82e1-50e1-9d54-7805d29e11a7
DOI: 10.1101/2025.07.11.664452

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