Article

Lung-mimicking click alginate-dECM model of breast cancer lung metastasis reveals the role of ECM mechanics in tumor growth dynamics and genomic instability

2026-01-08

Abstract excerpt

Metastatic breast cancer (BC) is the main cause of cancer-related death in women. Accumulating evidence highlights the prominent changes within the lung metastatic niche, resulting in stiffening of the extracellular matrix (ECM). The prevailing concept of cancer evolution encompasses the acquisition of beneficial traits as a consequence of genomic instability, yet it remains elusive to what extend altered lung ECM...

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Literature Corpus work: 61bb0537-ba9d-5e62-b5df-19d6be1162a1
DOI: 10.64898/2026.01.08.698349

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