Article

FH loss in RPE cells causes retinal degeneration in a human RPE-porcine retinal explant co-culture model

2021-07-26

Abstract excerpt

Age-related Macular degeneration (AMD) is a degenerative disease of the macula affecting the elderly population. Treatment options are limited, partly due to the lack of understanding of AMD pathology and the sparse availability of research models, that replicate the complexity of the human macula and the intricate interplay of the genetic, aging and life-style risk factors contributing to AMD. One of the main gen...

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Literature Corpus work: a4fe9393-b812-5658-bbd2-cd8e030f35c6
DOI: 10.1101/2021.07.26.453778

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