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Complement Factor H (Y402H) polymorphism for age-related macular degeneration alters retinal lipids

2026-01-07

Abstract excerpt

Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is associated with multiple risk factors and involves death of the retinal pigment epithelium (RPE). We investigated how the Y402H polymorphism of Complement Factor H (CFH) and cigarette smoke extract (CSE), major AMD genetic and environmental risks, affect lipid metabolism in RPE differentiated from induced pluripotent stem cel...

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Literature Corpus work
fdba5153-06bd-59e2-b723-d3dbceac7fac
DOI
10.64898/2026.01.06.697989
Open publication

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Complement Factor H (Y402H) polymorphism for age-related macular degeneration alters retinal lipidsDOI 10.64898/2026.01.06.697989
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