Article

Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver

2022-11-09

Abstract excerpt

Melanocortin 1 receptor (MC1-R) is widely expressed in melanocytes and leukocytes, and is thus strongly implicated in the regulation of skin pigmentation and inflammation. MC1-R mRNA has also been found in the rat and human liver, but its functional role has remained elusive. We hypothesized that MC1-R is functionally active in the liver and involved in the regulation of cholesterol and bile acid metabolism. We ge...

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Literature Corpus work: a47beaac-a61d-56da-b790-f26cd6c31e53
DOI: 10.1101/2022.11.08.515543

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