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Article

Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.

Hepatology (Baltimore, Md.) - 1 Feb 2015

Stiedl Patricia, McMahon Robert, Blaas Leander, Stanek Victoria, Svinka Jasmin, Grabner Beatrice, Zollner Gernot, Kessler Sonja M, Claudel Thierry, Müller Mathias, Mikulits Wolfgang, Bilban Martin, Esterbauer Harald, Eferl Robert, Haybaeck Johannes, Trauner Michael, Casanova Emilio

Abstract excerpt

UNLABELLED: Growth hormone (GH) resistance has been associated with liver cirrhosis in humans but its contribution to the disease remains controversial. In order to elucidate whether GH resistance plays a causal role in the establishment and development of liver fibrosis, or rather represents a major consequence thereof, we challenged mice lacking the GH receptor gene (Ghr(-/-), a model for GH resistance) by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25179284
DOI: 10.1002/hep.27408
PMCID: PMC4986903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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