Article

Non-viral vasculogenic reprogramming restores cognition and mitigates pathology in Alzheimer’s disease

2026-01-24

Abstract excerpt

Alzheimer’s Disease (AD) is characterized by progressive cognitive decline associated with amyloid-beta (Aβ) plaques, neurofibrillaiy tangles, inflammation, synaptic loss, and profuse neuronal death. Accumulating evidence demonstrates that cerebrovascular impairment precedes the emergence of neuropathological hallmarks, implicating vascular dysfunction as an early contributor to AD onset and progression. We invest...

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Literature Corpus work: a4460551-389d-5b4d-bb36-71b142fcfe56
DOI: 10.64898/2026.01.22.700900

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