Article

Vicious circle of amyloid and leptomeningeal macrophages evokes vascular dysfunction in CAA

2026-02-14

Abstract excerpt

<h4>ABSTRACT</h4> The subarachnoid space contains leptomeningeal arteries and resident immune cells known as subarachnoid macrophages (SAMs). In Alzheimer’s disease (AD) and related cerebral amyloid angiopathy, amyloid-β (Aβ) frequently accumulates around the leptomeningeal arteries. Nevertheless, the local immune responses and their functional consequences remain poorly understood. Using longitudinal intravital...

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Literature Corpus work: a524d380-c08c-5bf3-b10b-f202dd9f8458
DOI: 10.64898/2026.02.12.705483

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