Article

Linking cross-species trajectories of cerebrovascular remodeling in aging and Alzheimer’s disease to brain vessel transcriptome

2026-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Cerebrovascular remodeling driven by subtle molecular changes starts early in the asymptomatic stage of Alzheimer’s disease (AD). Despite progress in human vascular imaging and postmortem tissue analysis, there is limited data on the early features of small vessel reorganization, particularly in the context of cell-specific molecular drivers. This is largely because of the invasive nature of th...

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Literature Corpus work: d47abc65-319f-570e-978f-b33485b0083f
DOI: 10.64898/2026.03.06.710077

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