Article

A human brain vascular atlas reveals diverse cell mediators of Alzheimer’s disease risk

2021-04-27

Abstract excerpt

The human brain vasculature is of vast medical importance: its dysfunction causes disability and death, and the specialized structure it forms—the blood-brain barrier—impedes treatment of nearly all brain disorders. Yet, no molecular atlas of the human brain vasculature exists. Here, we develop Vessel Isolation and Nuclei Extraction for Sequencing (VINE-seq) to profile the major human brain vascular and perivascul...

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Literature Corpus work: ee8afe0c-6b8f-565c-a0bb-85e7efb7e3b6
DOI: 10.1101/2021.04.26.441262

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