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Chimeric antigen receptor-natural killer cell therapy: current advancements and strategies to overcome challenges

25 Apr 2024

Abstract excerpt

Chimeric antigen receptor-natural killer (CAR-NK) cell therapy is a novel immunotherapy targeting cancer cells via the generation of chimeric antigen receptors on NK cells which recognize specific cancer antigens. CAR-NK cell therapy is gaining attention nowadays owing to the ability of CAR-NK cells to release potent cytotoxicity against cancer cells without side effects such as cytokine release syndrome (CRS),...

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PMID: 38726000
DOI: 10.3389/fimmu.2024.1384039

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