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Pre-diagnosis plasma cell-free DNA methylome profiling up to seven years prior to clinical detection reveals early signatures of breast cancer

2023-02-01

Abstract excerpt

Profiling of cell-free DNA (cfDNA) has been well demonstrated to be a potential non-invasive screening tool for early cancer detection. However, limited studies have investigated the detectability of cfDNA methylation markers that are predictive of cancers in asymptomatic individuals. We performed cfDNA methylation profiling using cell-free DNA methylation immunoprecipitation sequencing (cfMeDIP-Seq) in blood coll...

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Literature Corpus work
a40a34e2-4600-5cb5-8a80-73caf9a59e6a
DOI
10.1101/2023.01.30.23285027
Open publication

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Pre-diagnosis plasma cell-free DNA methylome profiling up to seven years prior to clinical detection reveals early signatures of breast cancerDOI 10.1101/2023.01.30.23285027
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