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Circulating cell-free DNA-based epigenetic assay can detect early breast cancer

1 Dec 2016

Abstract excerpt

BACKGROUND: Circulating cell-free DNA (cfDNA) has recently been recognized as a resource for biomarkers of cancer progression, treatment response, and drug resistance. However, few have demonstrated the usefulness of cfDNA for early detection of cancer. Although aberrant DNA methylation in cfDNA has been reported for more than a decade, its diagnostic accuracy remains unsatisfactory for cancer screening. Thus,...

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PMID: 27993161
DOI: 10.1186/s13058-016-0788-z

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