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Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s disease

27 Sept 2018

Abstract excerpt

Stem cell transplantation offers a potentially transformative approach to treating neurodegenerative disorders. The safety of cellular therapies is established in multiple clinical trials, including our own in amyotrophic lateral sclerosis. To initiate similar trials in Alzheimer's disease, efficacious cell lines must be identified. Here, we completed a preclinical proof-of-concept study in the APP/PS1 murine...

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PMID: 30283042
DOI: 10.1038/s41598-018-33017-6

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