Article

p75 Neurotrophin Receptor Shapes the Dynamics of Adult Hippocampal Neurogenesis in Alzheimer's Disease

2025-10-22

Abstract excerpt

<title>Abstract</title> <p>Background Alzheimer’s Disease (AD) is a neurodegenerative disorder primarily characterized by memory loss and cognitive decline. The AD-driven impairment of adult hippocampal neurogenesis - the process of generating new neurons in the dentate gyrus - is strongly implicated in this cognitive failure. Adult Neurogenesis is dependent on neurotrophin signaling, with the p75 pan-neurotrophi...

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Literature Corpus work: 928861cd-855f-5eb6-ac17-6a2b7d7639a6
DOI: 10.21203/rs.3.rs-7790527/v1

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