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Stem Cell Therapies in Alzheimer’s Disease: Applications for Disease Modeling

8 Feb 2021

Abstract excerpt

-amyloid deposits, such as senile plaques, and intracellular aggregation of hyperphosphorylated tau, such as neurofibrillary tangles, remain the main neuropathological criteria for the diagnosis of AD. There is currently no effective treatment of the disease, and many clinical trials have failed to prove any benefits of new therapeutics. More recently, there has been increasing interest in harnessing the...

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PMID: 33558427
DOI: 10.1124/jpet.120.000324

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